Genetics & Epidemiology Peer Reviewed Articles
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PUBLICATIONS
2008
1. Cadwell KK, Whitehouse CA, Tarone RE, Tawn EJ (2008) Comparison of in vivo translocation frequencies with in vitro G2 radiosensitivity in radiation workers occupationally exposed to external radiation J. Radiol. Prot. 28 101-106.
2. Sigurdson AJ, Ha M, Bhatti P, Sram RJ, Beskid O, Tawn EJ, Whitehouse CA, Lindholm C, Nakano M, Kodama Y, Nakamura N, Vorobtsova I, Oestreicher U, Stephan G, Yong LC, Bauchinger M, Schmid E, Chung HW, Darroudi F, Laurence R, Voisin P, Barquinero JF, Livington G, Blakey D, Hayata I, Zhang W, Wang C, Bennett LM, Littlefield LG, Edwards AA, Kleinerman RA, Tucker JD (2008) International study of factors affecting human chromosome translocations Mutat. Res. 652 112-121.
3. Tawn EJ, Whitehouse CA, Holdsworth D, De Ruyck K, Vandenbulcke K, Thierens H (2008) mBAND analysis of chromosome aberrations in lymphocytes exposed in vitro to α-particles and γ-rays Int. J. Radiat. Biol. 84 1-7.
2007
4. Wilding CS, Curwen GB, Tawn EJ, Sheng X, Winther JF, Chakraborty R and Boice JD Jr (2007) Influence of polymorphisms at loci encoding DNA repair proteins on G2 chromosomal radiosensitivity Environmental and Molecular Mutagenesis 48 48-57.
5. Little MP, Tawn EJ, Tzoulaki I, Wakeford R, Hildebrandt G, Paris F, Tapio S, Elliott P (2007) A systematic review of epidemiological associations between low and moderate doses of ionizing radiation and late cardiovascular effects, and their possible mechanisms Radiat. Res. 169 99-109.
6. Tawn EJ, Whitehouse CA, De Ruyck K, Hodgson L, Vandenbulcke K, Thierens H (2007) The characterization and transmissibility of chromosome aberrations induced in peripheral blood lymphocytes by in vitro -particle radiation Radiat. Res. 168 666-674.
2006
7. Wilding CS, Trikic MZ, Hingston JL, Copplestone D and Tawn EJ (2006) Mitochondrial DNA mutation frequencies in experimentally irradiated compost worms, Eisenia fetida Mutat. Research 603 56-63.
8. Wilding CS, Cadwell K, Tawn EJ, Relton CL, Taylor GA, Chinnery PF and Turnbull DM (2006) Mitochondrial DNA mutations in individuals occupationally exposed to ionizing radiation Radiat. Res. 165 202-7.
9. Wilding CS, Rees GS, Relton CL and Tawn EJ (2006) Genotype profiles of Loci encoding DNA repair enzymes in newborn and elderly populations: no evidence of association with longevity Biogerontology 7 35-41.
10. Rees GS, Trikic MZ, Winther JF, Tawn EJ, Olsen JH, Rechnitzer C, Schrøder H, Guldberg P and Boice JD, Jr (2006) A pilot study examining germline minisatellite mutations in the offspring of Danish childhood and adolescent cancer survivors treated with radiotherapy Int. J. Radiat. Biol. 82 153-160.
11. Tawn EJ, Whitehouse CA and Riddell AE (2006) FISH chromosome analysis of plutonium workers from the Sellafield nuclear facility Radiat. Res. 165 592-597.
2005
12. Wilding CS, Relton CL, Rees GS, Tarone RE, Whitehouse CA and Tawn EJ (2005) DNA repair gene polymorphisms in relation to chromosome aberration frequencies in retired radiation workers Mutat. Res. 570 137-145.
13. Cowell JK, Morris JA and Tawn EJ (2005) Analysis of the RB1 gene in children with retinoblastoma having residential connections to West Cumbria, England J. Radiol. Prot. 25 89-92.
14. Tawn EJ and Whitehouse CA (2005) Chromosome intra- and inter-changes determined by G-banding in radiation workers with in vivo exposure to plutonium J. Radiol. Prot. 25 83-88.
15. Tawn EJ, Whitehouse CA, Winther JF, Curwen GB, Rees GS, Stovall M, Olsen JH, Guldberg P, Rechnitzer C, Schroder H and Boice JD, Jr. (2005) Chromosome analysis in childhood cancer survivors and their offspring - No evidence for radiotherapy-induced persistent genomic instability Mutat. Res. 583 198-206.
16. Relton CL, Pearce MS and Parker L (2005) The influence of erythrocyte folate and serum vitamin B12 status on birth weight Br J Nutr 93 593-9.
17. Whitehouse CA, Edwards AA, Tawn EJ, Stephan G, Oestreicher U, Moquet JE, Lloyd DC, Roy L, Voisin P, Lindholm C, Barquinero J, Barrios L, Caballin MR, Darroudi F and Formina J (2005) Translocation yields in peripheral blood lymphocytes from control populations Int. J. Radiat. Biol. 81 139-145.
18. Edwards AA, Lindholm C, Darroudi F, Stephan G, Romm H, Barquinero J, Barrios L, Caballin MR, Roy L, Whitehouse CA, Tawn EJ, Moquet J, Lloyd D and Voisin P (2005) Review of translocations detected by FISH for retrospective biological dosimetry applications Radiat. Prot. Dosim. 113 396-402.
19. Wakeford R and Tawn EJ (2005) The risk to health from low doses of ionising radiation Nuclear Future 01 03.
20. Thierens H, De Ruyck K, Vral A, De Gelder V, Whitehouse CA, Tawn EJ and Boesman I (2005) Cytogenetic biodosimetry of an accidental exposure of a radiological worker using multiple assays Radiat. Prot. Dosim. 113 408-414.
21. Ruyck K De, Wilding CS, Eijkeren M Van, Morthier R, Tawn EJ and Thierens H (2005) Microsatellite polymorphisms in DNA repair genes XRCC1, XRCC3 and XRCC5 in patients with gynecological tumors: Association with late clinical radiosensitivity and cancer incidence. Radiat. Res. 164 237–244.
22. Curwen GB, Winther JF, Tawn EJ, Smart V, Whitehouse CA, Rees GS, Olsen JH, Guldberg P, Rechnitzer C, Schroder H, Bryant PE, Sheng X, Lee HS, Chakraborty R and Boice JD, Jr (2005) G2 chromosomal radiosensitivity in Danish survivors of childhood and adolescent cancer and their offspring. Br. J. Cancer 93 1038-45.
2004
23. Relton CL, Daniel CP, Hammal DM, Parker L, Tawn EJ and Burn J (2004) DNA repair gene polymorphisms, pre-natal factors and the frequency of somatic mutations in the glycophorin-A gene among healthy newborns Mutat. Res. 545 49-57.
24. Relton CL, Wilding CS, Laffling AJ, Jonas PA, Burgess T, Binks K, Tawn EJ and Burn J (2004) Low erythrocyte folate status and polymorphic variation in folate-related genes are associated with risk of neural tube defect pregnancy Mol. Genet. Metab. 81 273-81.
25. Relton CL, Wilding CS, Pearce MS, Laffling AJ, Jonas PA, Lynch SA, Tawn EJ and Burn J (2004) Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population J. Med. Genet. 41 256-60.
26. Wilding CS, Relton CL, Sutton MJ, Jonas PA, Lynch SA, Tawn EJ and Burn J (2004) Thymidylate synthase repeat polymorphisms and risk of neural tube defects in a population from the northern United Kingdom Birth Defects Res. Part A Clin. Mol. Teratol. 70 483-5.
27. Winther JF, Boice JD Jr, Mulvihill JJ, Stovall M, Frederiksen K, Tawn EJ and Olsen JH (2004) Chromosomal abnormalities among offspring of childhood cancer survivors in Denmark: a population-based study Am. J. Hum. Genet. 74 1282-1285.
28. Rees GS, Daniel CP, Morris SD, Whitehouse CA, Binks K, Macgregor DH and Tawn EJ (2004) Occupational exposure to ionising radiation has no effect on T- and B-cell total counts or percentages of helper, cytotoxic and activated T-cell subsets in the peripheral circulation of male radiation workers Int. J. Radiat. Biol. 80 493-8.
29. Tawn EJ, Whitehouse CA and Tarone RE (2004) FISH chromosome aberration analysis on retired radiation workers from the Sellafield nuclear facility Radiat. Res. 162 249-56.
2003
30. Little MP and Tawn EJ (2003) Comments on 'Estimation of X ray overexposure in a childhood leukaemia cluster by means of chromosome aberration analysis' Radiat. Prot. Dosim. 103 77-9; author reply 79-81.
31. Tawn EJ, Whitehouse CA, Daniel CP, Tarone RE, Bothwell AM and Fisher A (2003) Somatic cell mutations at the glycophorin A locus in erythrocytes of radiation workers from the Sellafield nuclear facility Radiat. Res. 159 117-22.
32. Boice JD Jr, Tawn EJ, Winther JF, Donaldson SS, Green DM, Mertens AC, Mulvihill JJ, Olsen JH, Robison LL and Stovall M (2003) Genetic effects of radiotherapy for childhood cancer Health Phys. 85 65-80.
33. Smart V, Curwen GB, Whitehouse CA, Edwards A and Tawn EJ (2003) Chromosomal radiosensitivity: a study of the chromosomal G2 assay in human blood lymphocytes indicating significant inter-individual variability Mutat. Res. 528 105-10.
34. Tawn EJ and Whitehouse CA (2003) Stable chromosome aberration frequencies in men occupationally exposed to radiation J. Radiol. Prot. 23 269-278.
35. Relton CL, Wilding CA, Jonas PA, Lynch SA, Tawn EJ and Burn J (2003) Genetic susceptibility to neural tube defect pregnancy varies with offspring phenotype Clin. Genet. 64 424-428.
36. Tawn EJ and Whitehouse CA (2003) Persistence of translocation frequencies in blood lymphocytes following radiotherapy: implications for retrospective radiation biodosimetry J. Radiol. Prot. 23 423-430.
37. Relton CL, Jackson A and Burn J (2003) Folic acid - changes in women's knowledge Br. J. Midwif. 11 438-441.
2002
38. Relton CL, Daniel CP, Fisher A, Chase DS, Burn J and Tawn EJ (2002) Polymorphisms of the DNA repair gene XRCC1 and the frequency of somatic mutations at the glycophorin A locus in newborns Mutat. Res. 502 61-8.
39. Bryant PE, Gray L, Riches AC, Steel CM, Finnon P, Howe O, Kesterton I, Vral A, Curwen GB, Smart V, Tawn EJ and Whitehouse CA (2002) The G2 chromosomal radiosensitivity assay Int. J. Radiat. Biol. 78 863-6.
2001
40. Tawn EJ and Whitehouse CA (2001) Frequencies of chromosome aberrations in a control population determined by G banding Mutat. Res. 490 171-7.
41. Abrahamson S and Tawn EJ (2001) Risk of stillbirth in offspring of men exposed to ionising radiation J. Radiol. Prot. 21 133-44.
42. Haines GA, Hendry JH, Daniel CP and Morris ID (2001) Increased levels of comet-detected spermatozoa DNA damage following in vivo isotopic- or X-irradiation of spermatogonia Mutat. Res. 495 21-32.
43. Whitehouse CA and Tawn EJ (2001) No evidence for chromosomal instability in radiation workers with in vivo exposure to plutonium Radiat. Res. 156 467-75.
2000
44. Tawn EJ (2000) Stillbirths among offspring of male radiation workers Lancet 355 493-4.
45. Tawn EJ, Whitehouse CA, Holdsworth D, Morris S and Tarone RE (2000) Chromosome analysis of workers occupationally exposed to radiation at the Sellafield nuclear facility Int. J. Radiat. Biol. 76 355-65.
46. Tawn EJ, Whitehouse CA and Martin FA (2000) Sequential chromosome aberration analysis following radiotherapy - no evidence for enhanced genomic instability Mutat. Res. 465 45-51.
47. Bothwell AM, Whitehouse CA and Tawn EJ (2000) The application of FISH for chromosome aberration analysis in relation to radiation exposure Radiat. Prot. Dosim. 88
7-14.
48. Sorokine-Durm I, Whitehouse CA and Edwards AA (2000) The variability of translocation yields amongst control populations Radiat. Prot. Dosim. 88 93-99.
49. Daniel CP, Fisher A, Parker L, Burn J and Tawn EJ (2000) Individual variation in somatic mutations of the glycophorin-A gene in neonates in relation to pre-natal factors Mutat. Res. 467 153-9.
50. Wakeford R and Tawn EJ (2000) Paternal irradiation and leukemia in offspring Radiat. Res. 154 222-3.
51. Healey CS, Dunning AM, Teare MD, Chase D, Parker L, Burn J, Chang-Claude J, Mannermaa A, Kataja V, Huntsman DG, Pharoah PD, Luben RN, Easton DF and Ponder BA (2000) A common variant in BRCA2 is associated with both breast cancer risk and prenatal viability Nat. Genet. 26 362-4.